TNFSF10 and neoplasm: In relation to the role of NF-κB in cancer, it has been reported to be pro-apoptotic in the anti-tumor action of cisplatin in head and neck squamous cell carcinoma, in glioblastoma in TRAIL-induced cell death, and in adenocarcinoma cells infected with retroviruses or stimulated with TNF-α [25,26,27,28].