SCLC-A cell lines show a wide spectrum of sensitivity to platinum: high expression of SLFN11 in SCLC-A cell lines is correlated with higher sensitivity to both cisplatin and PARPis, whereas low expression of SLFN11 within this subgroup is accompanied by lower responsiveness to both platinum and PARP inhibition [19]. The gene discussed is SLFN11; the disease is small cell lung carcinoma.