Among these, the transcription factor GATA3 (SB010), prostaglandin D2 receptor (QAW039A), tyrosine kinase (imatinib), anti-IL-6 receptor (tocilizumab), and endothelin-A receptor (sitaxenten) have garnered attention for their potential impact on diverse molecular pathways associated with severe asthma [89,90,91,92,93]. The gene discussed is PTGDR; the disease is asthma.