The dysregulation of several adipokines metabolism, such as adiponectin, leptin, AFABP (adipocyte-specific fatty acid binding protein), tumour necrosis factor α (TNF-α), nesfatin, vaspin, chemerin and lipocalin, seems to be a potential factor involved in the pathophysiology of GDM [13,14,15]. Here, RARRES2 is linked to gestational diabetes.