results confirm that these unique genes are involved in CAC-related processes, including multiple cancer pathways (small and non-small cell lung cancer, pancreatic colorectal, endometrial, prostate cancer, bladder cancer, thyroid), signaling pathways (MAPK signaling, P13K-Akt signaling, p53 signaling, tumor necrosis factor (TNF) signaling, nuclear factor-kappa B (NF-κB) signaling, toll-like receptor (TLR) signaling, interleukins (IL)-17 signaling, and T-cell receptor signaling), apoptosis, and cellular senescence. This evidence concerns the gene TNF and thyroid gland disorder.