Figure 5E shows the 10 highest-ranking GO in terms of molecular function (MF), biological process (BP), and cellular component (CC). The prognosis-related genes were mostly related to tubulin, microtubule, actin, guanyl-nucleotide exchange factor, GTPase activator, rho GTPase, ras GTPase, small GTPase, rho guanyl-nucleotide exchange factor, and ras guanyl-nucleotide exchange factor activities. KEGG enrichment analysis indicated that these genes were related to cancer-related pathways, such as pancreatic cancer, TGF-β, focal adhesion, and Ras signaling (Figure 5F). This evidence concerns the gene TGFB1 and cancer.