Upregulation of MALAT1 negatively impacts prognosis in different types of cancers, including pancreatic cancer, hepatocellular carcinoma, nasopharyngeal carcinoma, colorectal cancer, breast cancer, osteosarcoma, gastric cancer (GC), lung cancer and esophageal squamous cell carcinoma (ESCC) [9]. Here, MALAT1 is linked to esophageal squamous cell carcinoma.