Platelet-derived growth factor receptor beta (PDGFRB), ITGA3, COL6A1, and p21 (RAC1)-activated kinase 4 (PAK4) were included in the GO term “Focal adhesion”, in which DEGs were upregulated in patients with non-emphysematous COPD. The gene discussed is COL6A1; the disease is chronic obstructive pulmonary disease.