TGF-1 and lactate levels of endometriosis patients are significantly higher than in normal females, and, in particular, the lesions of the disease are highly expressed in glycolytic-related genes, such as HIf1-α, Glut1, Pdk1, and Ldha, as well as the expression of glycolytic related genes; the glycolytic metabolism of the heterotopic endometrium was transferred to the warfarin effect [46,47]. The gene discussed is PDK1; the disease is endometriosis.