Common examples are HER2 in breast and gastric cancers, EGFR in lung, colorectal, and head and neck cancers, KRAS in colorectal, pancreatic, and lung adenocarcinoma, BRAF in melanoma and colorectal cancer, ALK in some NSCLC cases, and PSA as a prostate cancer biomarker. The gene discussed is KLK3; the disease is Familial prostate cancer.