In the present study, we also found that the colitis mice presented similar results with lower frequencies of mTreg (CD4+Foxp3+, CD4+CCR7+Foxp3+, CD4+CCR7−Foxp3+) cells and higher mTh17 (CD4+CCR6+, CD4+CCR7+CCR6+, CD4+CCR7−CCR6+) cells. This evidence concerns the gene CD4 and colitis.