HGF and hepatocellular carcinoma: EEDK can also inhibit hepatocyte growth factor (HGF)-mediated cell migration and invasion, weaken HGF-mediated JNK/C-Jun activation, and reduce HGF receptor Met activity, suggesting that EEDK may treat hepatocellular carcinoma by inhibiting the HGF/Mesenchymal-epithelial transition factor signaling pathway [100].