After 24 h, [89Zr]Zr-PSMA-DFO displayed much higher ratios between the tumor and the surrounding areas (tumor/blood: 309 ± 89, tumor/muscle: 450 ± 38) in LNCaP tumor xenografts when compared to [68Ga]Ga-PSMA-11 (tumor/blood: 112 ± 57, tumor/muscle: 58 ± 36) or [18F]F-JK-PSMA-7 (tumor/blood: 175 ± 30, tumor/muscle: 114 ± 14) after only 4 h (p < 0.01). This evidence concerns the gene FOLH1 and neoplasm.