Currently, few studies have investigated the effect of probiotics on insulin-related gene expression and lipid metabolism; however, there is some published information that may be related to this, such as the study by Chon et al. [33], where PPAR-γ polymorphisms were found to be highly correlated with the occurrence of GDM in pregnant women; therefore, probiotics, due to their beneficial actions on PPAR-γ, such as the probiotic capsule administered in the study by Babadi et al. [16], prove to be useful in controlling metabolic profiles in women with GDM. This evidence concerns the gene PPARG and gestational diabetes.