The meta-analysis showed a significantly reduced postprandial glucose peak and plasma insulin in patients with diabetes consuming DSF high in MUFA vs. those consuming STDF and demonstrated a reduction in glycemic variability (improved glycemic control), reduced HbA1c levels (improved long-term glycemic control), lower insulin doses (reduced use of medication), and improved lipid metabolism (less cardiovascular risk) [101]. The gene discussed is INS; the disease is diabetes mellitus.