The in vitro antineoplastic effect of miR-148a-3p overexpression also occurs through mitochondrial impairment, lipid peroxidation, and ferroptosis sustained by the Acyl CoA synthetase long-chain family member 4 (ACSL4)/transferrin receptor (TFRC)/Ferritin axis and direct solute carrier family seven-member 11 (SLC7A11) downregulation in the CRC model [50]. Here, ACSL4 is linked to colorectal carcinoma.