TGFB1 and Hepatic fibrosis: The soybean exosome-like nanoparticles (ELNs)-derived miR-5781 is able to modulate the inflammatory response by targeting IL-17A [62], while miR-159a might prevent hepatic fibrosis suppressing glycogen synthase kinase-3β (GSK-3β)-mediated NF-κB and TGF-β1 pathways, thus impairing TGF-β1- and platelet-derived growth factor (PDGF)-related hepatic stellate cell activation [69].