TNF and type 2 diabetes mellitus: In the first six months of lactation, miR-181a and b, miR-155, miR-125b, and the cluster miR-17-92 actively regulate the T- and B-cell maturation and the tumor necrosis factor α (TNF-α) activation, modulating the immune response of the baby [38], while miR-22-3p counteracts the development of insulin resistance and the onset of T2DM, attenuating the Wnt pathway [37].