IL1B and osteosarcoma: More recently, Ju et al. (2021) demonstrated, using an IL-1β-activated human osteosarcoma cell line (SW1353), that scutellarin inhibits the IL-1β-activated MAPK/NF-κB signaling pathway, as well as regulating the PI3K/AKT/mTOR signaling pathway, as has already been demonstrated.