Table 3 showcases 22 key genes identified in our analysis, each potentially contributing to the genetic basis of MetS in our study population. These genes include CETP, LPL, APOA5, SIK3, ZPR1, APOC1, BUD13, MLXIPL, TOMM40, GCK, YKT6, RPS6KB1, FTO, VMP1, TUBD1, BCL7B, C19orf80 (ANGPTL8), SIDT2, SENP7, PAFAH1B2, DOCK6, and FOXA2. The Manhattan plot presented in Figure 2 visually represents the genetic information of these genes, providing a comprehensive overview of their significance in the context of MetS. The gene discussed is SIK3; the disease is metabolic syndrome.