As expected, feeding an HF diet to the mothers for 6 weeks promoted an increase in basal glycemia (basal glycemia: NC mothers = 69.14 ± 1.792; HF mothers = 78.88 ± 3.573, mg/dL, p < 0.05) and a drastic decrease in insulin sensitivity (kITT: NC mothers = 4.864 ± 0.3957; HF mothers = 1.849 ± 0.3188, % glucose/min, p < 0.0001) without significantly affecting glucose tolerance (Table 1). Here, INS is linked to hydrops fetalis.