IL10 and neoplasm: However, in the present study, we detected IL-10 only in fatty tissue, where its level was lowest in calcitriol-treated old mice, in accordance with the results of the study by Wang et al. We observed increased IL-10 levels in tumor tissue of young mice following treatment with calcitriol in our previous study conducted in mice bearing 4T1 mammary gland tumors [22], whereas no such effect was noted in old mice [39].