VEGFA and central nervous system cancer: It was also found that the treatment inhibited the permeability, proliferation, migration, and formation of VEGF-induced tubules in human umbilical vein endothelial cells [48] to reduce the proliferation of C6 glioma cells, promoting antiangiogenic processes [49] and inhibit the proliferation of Caco2 human colon adenocarcinoma cells [50].