The qPCR analysis showed that the myofibroblast activation in response to TGF-β was significantly reduced in the presence of Hylach and HA since the α-SMA mRNA level of control and IPF human fibroblasts were downregulated (Figure 4a, p < 0.001 and p < 0.0001). This evidence concerns the gene TGFB1 and idiopathic pulmonary fibrosis.