IL13 and glioblastoma: The PRECISE study was the first phase III clinical trial, which compared CED of cintredekin besudotox (a recombinant protein consisting of interleukin-13 (IL-13) and a truncated form of Pseudomonas exotoxin (PE38QQR) 96 h after surgical resection with carmustine wafers placed at the time of surgery in 296 adult patients with glioblastoma multiforme at first recurrence.