However, L3MBTL3 expression was downregulated in breast cancer (BRCA), cervical cancer (CESC), kidney chromophobe (KICH), Pheochromocytoma and Paraganglioma (PCPG), thyroid cancer (THCA), and uterine corpus endometrial carcinoma (UCEC) (Figure 1A). Here, L3MBTL3 is linked to pheochromocytoma-paraganglioma.