Similarly, Mfotie Njoya et al. [70] showed that Croton gratissimus leaf extract exhibited cytotoxic effects on various cancer lines (A549, Caco-2, HeLa, MCF-7) and inhibited cancer cell growth through induction of caspase-3 (casp-3)/caspase-7 (casp-7) activation, with the highest induction (1.83-fold change) obtained on HeLa cells. The gene discussed is CASP3; the disease is cancer.