By analysing multiple online datasets and conducting in vitro work on pancreatic cancer cells, STRN1 and STRN3 were found to have upregulated expression in pancreatic tumour tissues and were associated with poor patient survival, in contrast to PPP2R1B, a scaffolding subunit of PP2A whose downregulation was shown to promote EMT [109]. The gene discussed is PPP2R1B; the disease is pancreatic neoplasm.