We found 16 cases (22%) positive for PD-L1 (CPS ≥ 5) with the highest prevalence amongst GC EBV(+) (40%) and GC dMMR (33%), followed by GC GS (21%), GC EMT (20%) and GC CIN (17%). This evidence concerns the gene CD274 and cervical squamous intraepithelial neoplasia.