Other significant biomarkers that are differentially expressed in kidney cancer include Aldolase A, Fructose-Bisphosphate (ALDOA), Collagen Type XVIII Alpha 1 Chain (COL18A1), Cytochrome C Oxidase Subunit 6B1 (COX6B1), Alpha-B Crystallin (CRYAB), Fatty Acid-Binding Protein 1 (FABP1), Phosphoenolpyruvate Carboxykinase 2, Mitochondrial (PCK2), Phosphatidylethanolamine-Binding Protein 1 (PEBP1), and Pyruvate Kinase Muscle (PKM). This evidence concerns the gene PKM and kidney cancer.