Here, we further categorized the original cohort of 41 AML patients into more refined subgroups, considering not only relapse categories but also incorporating the FAB-M1/M2 and FAB-M4/M5 classification subgroups (i.e., morphological signs of AML cell differentiation), as well as NPM1 mutation and cytogenetically normal AML. This evidence concerns the gene NPM1 and acute myeloid leukemia.