WEE1 and liver cancer: To analyze the response character of generated liver cancer cell lines and their capability to be used for drug screenings in vitro, we applied classical chemotherapeutic drug 5-FU, the tyrosine-kinase inhibitor Sorafinib, the protein-kinase inhibitor Axitinib, and interferon-alpha to these the four generated liver cancer cells, compared to immortalized cell lines Hep3B and HepG2H1.3.