Table 1 presents eight mutations in cancer-related genes, including frameshift mutations in ARID2 and CDKN2A; splice mutations in SATB2 and SMARCA4; and missense mutations in NOTCH3, STAG2, TET2 and WNT7A, all of which are present both in the primary tumor and in the cell line. A complete description of all WES results is presented in Table S2. PCR Sanger sequencing confirmed the inactivating mutations in SMARCA4 and CDKN2A (Figure 7), whereas no presence of HPV DNA was detected. The gene discussed is SATB2; the disease is cancer.