Considering the key role of the fibroblast growth factor receptor 1/phosphatidylinositol 3-kinase/protein kinase B (FGFR1/PI3K/AKT) pathway in T2DM, Xu et al. [24] explored the possible mechanism of GPS on lipid and glucose metabolism through its effects on the FGFR1/PI3K/AKT pathway in human hepatocellular carcinoma (HepG2) cells. This evidence concerns the gene FGFR1 and type 2 diabetes mellitus.