We observed significant immunoreactivity of α-SMA in the renal tissue of GWI+ AB mice only (Figure 7A,C, p < 0.001 between the GWI+ AB and control, GWI, and AB group), whereas no significant α-SMA immunoreactivity was observed in GWI mice (Figure 7A,C, p = 0.41 between the GWI and control group; p > 0.99 between the GWI and AB group) indicating that prolonged exposure to antibiotics amplifies the effects of GW chemicals, resulting in the development of a pathology resembling renal fibrosis. The gene discussed is ACTA1; the disease is renal fibrosis.