A TERT mutation identification could not be sufficient to assume that the tumor will behave as glioblastoma, IDH-wildtype (WHO CNS grade 4) as proposed in the cIMPACT-NOW update 6 [40] and it may be too late for the results of this paper to be incorporated in the upcoming 2021 WHO classification for CNS Tumor. Here, TERT is linked to glioblastoma.