The three OSA cell lines showed downregulated gene expression of IL1R2, IL2, JAK2 and IL13RA1 and showed upregulated expression of genes including CXCL8, IL6, CXCL10, CCL5, SPP1, OAS3, HBEGF, CD70 and IL15. Here, HBEGF is linked to obstructive sleep apnea syndrome.