According to these findings, Lactobacillus plantarum EPS H31-2 may effectively inhibit pancreatic amylase activity, which lowers blood glucose levels in type 2 diabetes (T2DM) patients, indicating that it may be utilized to both prevent and treat diabetes [236].In a high-fat diet and streptozotocin-induced type 2 diabetes in mice, a mixture of multiple Lactobacillus species reduced fasting blood glucose (FBG), hemoglobin A1c (HbA1C), and leptin levels and improved glucagon-like peptide-1 (GLP-1) levels [237]. The gene discussed is LEP; the disease is type 2 diabetes mellitus.