Levan, a polysaccharide derived from Bacillus licheniformis, was found to be efficient in preventing hyperglycemia and oxidative stress induced by diabetes in adult rats, suggesting that adding levan to the diet may help prevent diabetes-related molecular abnormalities such as blood glucose levels, improvement in peripheral sensitivity to residual insulin, and activation of Langerhans islets [233]. The gene discussed is INS; the disease is diabetes mellitus.