EGFR and chorioamnionitis: Pathway overrepresentation analysis of genes differentially expressed in LPS-exposed fetuses compared to control showed that genes suppressed by chorioamnionitis were associated with cholinergic synapse, dopaminergic synapse, and Wnt signaling, and genes induced by LPS were associated with ErbB signaling pathway and glutamatergic synapse suggesting that LPS suppressed developmental pathways and synapse formation in Purkinje cells (Fig. 3e).