These mice were xenografted with MKN-28.sh-PHB2 and MKN-28.sh-scramble control cells through subcutaneous transplantation, which led to a significant reduction in tumour growth in MKN-28.sh-PHB2 compared to MKN-28.sh-scramble control groups (Fig. 2I-K), accompanied by a decrease in cell proliferation within the tumours as indicated by the proportion of Ki67-expressing cells (Fig. 2L). Here, MKI67 is linked to neoplasm.