Next, Venn diagram showed that common 22 prognostic favorable genes between the up-regulated genes in FTO depleted AGS cells and prognostic favorable genes of GC patients, including TOE1, KCNQ1, SLC35A2, MFSD12, ENTPD8, TFDP1, MYO5C, USP43, CCN0, TRIM29, FAM83H, CLDN7, LRRC26, LRRC61, CUL4A, CD46, MSI2, ENTPD2, TNFAIP2, BICDL1, FAM83G, SLC52A3 (Fig. 4A). This evidence concerns the gene ENTPD8 and gastric cancer.