Studies have shown that the eukaryotic translation initiation factor 3H subunit (EIF3H), as a deubiquitinase, has a tumor-promoting function via the Wnt/β-catenin signaling pathway in intrahepatic cholangiocarcinoma cells47, and promotes Snail-mediated EMT process in esophageal squamous cell carcinoma48. The gene discussed is EIF3H; the disease is neoplasm.