To investigate the clinical significance of TRIM22 and PHLPP2 in HCC, we analyzed their expression levels in patients with HCC, as deposited to the International Cancer Genome Consortium Liver Cancer-RIKEN Japan (ICGC-LIRI-JP) (Fig. 6A) and TCGA-LIHC (Fig. 6B) databases. This evidence concerns the gene TRIM22 and hepatocellular carcinoma.