CAMP and rosacea: Aberrant microbial activity is also thought to be pathogenic in rosacea, a chronic skin inflammatory condition with multifactorial etiology.36 Dysbiotic colonization in rosacea is believed to drive a heightened host defense response encompassing enhanced anti-microbial peptide generation and immune cell recruitment.37 Compared to normal skin, patients with rosacea harbor more mast cells.38 Consistent with this, studies in murine models have demonstrated the importance of mast cells in rosacea-like skin inflammation induced by intradermal injection of the cathelicidin LL-37.