Upon training an ML classifier only on human BBS genes and predicting genes in all model species, we observed that the top-ranked genes [Table E in S1 File], biological processes [Table F in S1 File], and phenotypes in the model species are relevant to cilium function and manifestations of the BBS disorder such as rod/cone dystrophy, polydactyly, and hypogonadism [Table G in S1 File]. The gene discussed is BBS2; the disease is Cone rod dystrophy.