Few studies have shown that KNSTRN plays an important role in tumors (Xiong et al. 2021; Deng et al. 2021; Lee et al. 2016; Jaju et al. 2015; Knstrn Deemed an Oncogene 2014), but the present study is the first to reveal the functions of KNSTRN in breast cancer. Here, KNSTRN is linked to breast cancer.