The results showed that high KNSTRN expression was significantly associated with a worse outcome for patients with breast cancer in T2 (HR = 1.62, p = 0.031), N1 (HR = 1.74, p = 0.04), N3 (HR = 5.96, p = 0.004), M0 (HR = 1.51, p = 0.023), Stage II (HR = 1.64, p = 0.04), Stage III (HR = 2.70, p = 0.016), and those over 60 years of age (HR = 1.85, p = 0.008) (Table 2). This evidence concerns the gene KNSTRN and breast cancer.