Similar findings were detected for AT100, showing almost exclusive detection of pT212/S214 tau in the insoluble fraction of AD cases, showing higher detection compared to all other groups (vs AD-LB, p = 0.048; vs PDD, p < 0.01; vs controls, p < 0.01), while pT212/S214 was also detected in AD-LB cases but to a much lesser extent. The gene discussed is MAPT; the disease is Alzheimer disease.