Therefore, it would be interesting to evaluate GAS5-AS1 and GAS5 M6A modification levels and the amount of both ALKBH5 and YTHDF2 in colonic biopsies of IBD patients to further investigate the molecular mechanisms at the basis of the different correlation between GAS5 and its GAS5-AS1 detected in the inflamed and non-inflamed colon samples. This evidence concerns the gene GAS5 and inflammatory bowel disease.