MYCN and neuroblastoma: In line with an increased RAPTOR dependency of cells with a DDX1-MYCN coamplification, dependency scores for RAPTOR significantly negatively correlated with the DDX1 copy-number in MYCN-amplified neuroblastoma cell lines (Fig. 3A, Pearson coefficient = −0.5996, P = 0.0152; Supplementary Fig. S3C and S3D).