MGMT status did not influence growth rate or directionality in the pretreatment setting of our studied population, corroborating current literature findings on phenotypical tumor biology.15 Additionally, it was observed that the patients included in the study exhibited a distinct tumor occurrence location in the temporoparietal lobe, deviating from the previously documented descriptions in the existing literature, and exhibiting a preference for frontal lobe incidence. The gene discussed is MGMT; the disease is neoplasm.