AKT1 and idiopathic pulmonary fibrosis: Pathways enriched in track FibAlv-4 include: in Path A, Collagen and Extracellular Matrix (ECM) pathways49; in Path B, the PI3K-Akt-mTOR signaling pathway and the focal adhesion pathway, both hallmarks of IPF fibroblasts50–52 (Fig. 3b); and in Path C, SLIT2, a known marker of IPF42.