PTK2 and metabolic dysfunction-associated steatohepatitis: Fak, one of the core genes in the focal adhesion pathway, was found to downregulate the primary ligand MICA of NKG2D immune receptors through the Fak/Src pathway, thereby weakening susceptibility to NK cell-mediated killing.33 In our study, it showed non-statistical increment in the NASH-FMT group and non-statistical reduction in the Uni-FMT and Bifi-FMT groups.